In early September, the drug giant Johnson & Johnson was ordered to pay out $37.3 million on yet another cancer case relating to the asbestos found in a talc-based baby powder. Louisville residents should know that the four plaintiffs allegedly used the baby powder and developed mesothelioma as a result: a rare, aggressive cancer with few effective treatment options.
Many pleural mesothelioma patients undergo immunotherapy, but some will relapse. Louisville residents should know that there is a drug called vorinostat that may help relapsed patients. This is according to a study from Tampa's Moffitt Cancer Center. Vorinostat is an inhibitor of the enzyme histone deacetylase and can change protein expression in cells as well as boost the immune system.
Treatment options exist in Kentucky that have the potential to increase survival times for people with mesothelioma. Chemotherapy centered around the drug Alimta has become the standard course of treatment for mesothelioma patients, but a study of 910 people with the disease showed that older patients received this treatment less often than younger people with the diagnosis.
A study by university researchers indicates that the risk for a certain type of mesothelioma never drops once the person has been exposed to asbestos. People in Louisville who have previous exposure to asbestos might be interested in the findings, which showed that pleural mesothelioma risk might level off over the course of decades, but the risk of peritoneal mesothelioma is never reduced. Even after more than 40 years following exposure, the risk continues to grow.
Mesothelioma has always been rarer among women than among men, but the incidence rate among women is still nothing to ignore. While there are 1.93 cases of mesothelioma per 100,000 men in the U.S., there are 0.41 per 100,000 women. Residents of Louisville should know that the number one cause of mesothelioma in both men and women is asbestos exposure.
Various treatments for mesothelioma have been developed, yet none have been found to extend the lives of mesothelioma patients beyond a few months. Residents of Kentucky should know that the use of immune checkpoint inhibitors is also ineffective, the reason being that mesothelioma can keep dendritic cells, which are immune system cells, from activating the T-cells that can attack the cancer.
Louisville residents should be aware that mesothelioma, especially pleural mesothelioma, is an aggressive cancer. What makes matters worse is that most people are diagnosed in its late stages and thus have a low survival rate. However, Israeli researchers have found that a new cancer blood test could identify early-stage mesothelioma.
Every year in the U.S., there are approximately 3,000 new cases of mesothelioma. This disease, which usually arises from prolonged exposure to asbestos, equally affects men and women regardless of age or profession. However, Louisville residents should know that it may take years or even decades before they are ever diagnosed with it.
Mesothelioma patients in Kentucky may soon be receiving a different recommended treatment plan from their oncologist. A new study found that prophylactic radiotherapy may not be a successful treatment option for this form of cancer. Prophylactic radiotherapy has been used for over 20 years in the treatment of pleural mesothelioma.
Kentucky residents who have a nonexpandable lung may have malignant mesothelioma. The lungs of people with malignant mesothelioma are unable to expand to the chest wall, which makes it difficult for them to inhale and exhale normally. This inability of the lung to expand properly can be the result of fibrotic changes in the chest cavity and of inflammation. According to researchers who examined patients who were diagnosed with malignant mesothelioma, a nonexpendable lung in cancer patients who can be an accurate indicator of patient mortality.